Calcineurin autoinhibitory peptide (TFA)
Calcineurin autoinhibitory peptide (TFA)
SKU:QM-0167419
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Product Details
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Description
Calcineurin autoinhibitory peptide TFA is a selective inhibitor of Ca2+/calmodulin-dependent protein phosphatase (calcineurin), with an IC50 of ~10 μM. Calcineurin autoinhibitory peptide TFA could protect neurons from excitatory neuronal death[1][2].
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Molecular Formula
C124H205N39O39S2.xC2HF3O2
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Smiles
OC(C(F)(F)F)=O.O=C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](CCSC)C(N2[C@@H](CCC2)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H]3N(CCC3)C([C@H](CCSC)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(O)=O)NC([C@H](CC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CCCNC(N)=N)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@H](CO)NC([C@H]([C@H](O)C)NC([C@@H](N)[C@@H](C)CC)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
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Target
Phosphatase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Calcineurin autoinhibitory peptide (TFA)
Calcineurin autoinhibitory peptide (TFA) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.