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CB1 antagonist 6
CB1 antagonist 6
SKU:QM-0015547
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Product Details
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Description
CB1 antagonist 6 (Compound 11jE2) is an orally active CB1R antagonist, with an IC50 value of 23 nM. CB1 antagonist 6 significantly reduces food intake and body weight, improves glucose tolerance and insulin resistance, and decreases serum ALT and AST levels in diet-induced obese (DIO) mice, demonstrating hepatoprotective effects. CB1 antagonist 6 can be used for the study of metabolic syndrome (obesity, diabetes) [1].
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Molecular Formula
C30H24ClF3N6O2S
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Molecular Weight
625.06
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Smiles
O=S(C1=CC=C(C=C1)C(F)(F)F)(/N=C(N2CC[C@@H](C(C3=CC=C(C=C3)Cl)=N2)C4=CC=CC=C4)\N=C(C5=NC=CC=C5)/N)=O
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Target
Cannabinoid Receptor
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Isoform
CB1
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Shipping Conditions
Room temperature
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CB1 antagonist 6
CB1 antagonist 6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.