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CCR2 antagonist 4 [CAS 226226-39-7]
CCR2 antagonist 4 [CAS 226226-39-7]
SKU:QM-0112972-01
£238.32 GBP
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Product Details
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Description
CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM[1].
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CAS Number
[226226-39-7]
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Molecular Formula
C21H21ClF3N3O2
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Molecular Weight
439.86
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Smiles
O=C(NCC(N[C@H]1CN(CC2=CC=C(Cl)C=C2)CC1)=O)C3=CC=CC(C(F)(F)F)=C3
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Target
CCR
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Isoform
CCR2
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Purity
99.89
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Solubility
DMSO : ≥ 50 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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CCR2 antagonist 4 [CAS 226226-39-7]
CCR2 antagonist 4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.