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CCR6 inhibitor 1 [CAS 2437547-04-9]
CCR6 inhibitor 1 [CAS 2437547-04-9]
SKU:QM-0137652-01
£501.98 GBP
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Product Details
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Description
CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM) . CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer[1].
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CAS Number
[2437547-04-9]
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Molecular Formula
C24H23F3N4O3S
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Molecular Weight
504.52
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Smiles
O=S([C@H](CC1)CC[C@@H]1NC2=NC=C(C(F)(F)F)C=C2)(C3=CC=C(C4=CC=NC(C(N)=O)=C4)C=C3)=O
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Target
CCR
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Isoform
CCR6; CCR7
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Purity
99.6
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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CCR6 inhibitor 1 [CAS 2437547-04-9]
CCR6 inhibitor 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.