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Cdk1/2 Inhibitor III [CAS 443798-55-8]

Cdk1/2 Inhibitor III [CAS 443798-55-8]

Size

QM-0137514-01

£238.32 GBP
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Product Details

  • Description

    Cdk1/2 Inhibitor III (compound 3n) is a highly potent and selective Cdk1/cyclin B and Cdk2/cyclin A inhibitor of with IC50s of 0.6 nM and 0.5 nM, respectively. Cdk1/2 Inhibitor III shows selectivity over VEGF-R2 (IC50 of 32 nM), GSK-3β (IC50 of 140 nM), and a other kinases. Cdk1/2 Inhibitor III inhibits in cell proliferation with IC50s of 20 nM, 35 nM and 92 nM for HCT-116, HeLa, and A375 cells, respectively[1].

  • CAS Number

    [443798-55-8]

  • Molecular Formula

    C15H13F2N7O2S2

  • Molecular Weight

    425.44

  • Smiles

    S=C(N1N=C(N)N=C1NC2=CC=C(S(=O)(N)=O)C=C2)NC3=C(F)C=CC=C3F

  • Target

    CDK

  • Isoform

    CDK1; CDK2

  • Purity

    99.69

  • Solubility

    DMSO : 125 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
1 mgQM-0137514-01
1 mgQM-0137514-01
£238.32/ea		 £0.00
£238.32/ea £0.00
5 mgQM-0137514-02
5 mgQM-0137514-02
£803.30/ea		 £0.00
£803.30/ea £0.00
10 mgQM-0137514-03
10 mgQM-0137514-03
£1,255.28/ea		 £0.00
£1,255.28/ea £0.00
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Cdk1/2 Inhibitor III [CAS 443798-55-8]

Cdk1/2 Inhibitor III is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.