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Cot inhibitor-2 [CAS 915363-56-3]

Cot inhibitor-2 [CAS 915363-56-3]

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SKU:QM-0155862-01

£294.22 GBP
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  • Description

    Cot inhibitor-2 is a potent, selective and orally active cot (Tpl2/MAP3K8) inhibitor with an IC50 of 1.6 nM. Cot inhibitor-2 inhibts TNF-α production in LPS-stimulated human whole blood with an IC50 of 0.3 μM[1].

  • CAS Number

    [915363-56-3]

  • Molecular Formula

    C26H25Cl2FN8

  • Molecular Weight

    539.43

  • Smiles

    N#CC1=C(C2=CC(NCC3=CN(N=N3)C4CCN(CC4)CC)=CC(Cl)=C2N=C1)NC5=CC=C(F)C(Cl)=C5

  • Target

    MAP3K

  • Purity

    99.65

  • Solubility

    DMSO : 40 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0155862-01
5 mgQM-0155862-01
£294.22/ea
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£294.22/ea £0.00
10 mgQM-0155862-02
10 mgQM-0155862-02
£438.80/ea
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25 mgQM-0155862-03
25 mgQM-0155862-03
£865.26/ea
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£865.26/ea £0.00
50 mgQM-0155862-04
50 mgQM-0155862-04
£1,354.91/ea
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£1,354.91/ea £0.00
100 mgQM-0155862-05
100 mgQM-0155862-05
£2,139.80/ea
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£2,139.80/ea £0.00

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Cot inhibitor-2 [CAS 915363-56-3]

Cot inhibitor-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.