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Cystatin B agonist 1
Cystatin B agonist 1
SKU:QM-0013019
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Product Details
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Description
Cystatin B agonist 1 is an orally active MMP-2/9 inhibitor. Cystatin B agonist 1 exhibits inhibitory effects with IC50 values of 3.95 and 3.43 μM against U87 and T98G cells, respectively. Cystatin B agonist 1 induces the cell-cycle arrest at S phase, inhibits angiogenesis, and suppresses migration and invasion of MG cells. Cystatin B agonist 1 inhibits tumor growth in U87 MG xenograft model. Cystatin B agonist 1 can be used for the study of malignant glioma (MG) [1].
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Molecular Formula
C19H20O6
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Molecular Weight
344.36
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Smiles
C=C1C(O[C@H]2CC3=C[C@@H](OC3=O)C/C(C)=C/[C@H]([C@H]12)OC(C4CC4)=O)=O
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Target
Cadherin; MMP
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Shipping Conditions
Room temperature
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Cystatin B agonist 1
Cystatin B agonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.