DGAT-1 inhibitor 2 (Standard) [CAS 942999-61-3]
DGAT-1 inhibitor 2 (Standard) [CAS 942999-61-3]
SKU:QM-0017425
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Product Details
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Description
DGAT-1 inhibitor 2 (Standard) is the analytical standard of DGAT-1 inhibitor 2. This product is intended for research and analytical applications. DGAT-1 inhibitor 2 is an orally active DGAT-1 inhibitor with IC50 values of 15 nM and 9 nM for human DGAT-1 and rat DGAT-1, respectively. DGAT-1 inhibitor 2 increases ROS concentration, GRP78, and PERK protein abundance. DGAT-1 inhibitor 2 increases SREBF1, CPT1A, and MTTP mRNA in fatty acid-treated cells. DGAT-1 inhibitor 2 improves obesity[1][2].
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CAS Number
[942999-61-3]
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Molecular Formula
C24H28N4O3
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Molecular Weight
420.5
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Smiles
O=C(O)CC12CCC(CC1)(CC2)C3=CC=C(C=C3)C4=NC5=C(N)N=CN=C5OC4(C)C
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Target
Acyltransferase; HSP; PERK; Reactive Oxygen Species (ROS) ; Reference Standards
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Shipping Conditions
Room temperature
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DGAT-1 inhibitor 2 (Standard) [CAS 942999-61-3]
DGAT-1 inhibitor 2 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.