(E/Z) -ABP/PPAR modulator 1
(E/Z) -ABP/PPAR modulator 1
SKU:QM-0011024
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Product Details
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Description
(E/Z) -ABP/PPAR modulator 1 is a mixture of the E and Z isomers of ABP/PPAR modulator 1. ABP/PPAR modulator 1 is an orally active FABP and PPAR multiple modulator (IC50s of 0.65 μM and 1.08 μM for FABP1 and FABP4, EC50 s of 9.19 μM, 2.20 μM and 1.58 μM for PPARα, PPARγ and PPARδ). ABP/PPAR modulator 1 has potent anti-metabolic dysfunction-associated steatohepatitis (MASH) activity. ABP/PPAR modulator 1 dose-dependently ameliorates multiple pathological characteristics of fatty liver in WD + Carbon tetrachloride-induced MASH mice model[1].
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Molecular Formula
C33H39NO7
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Molecular Weight
561.67
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Smiles
COC1=CC=C(/C=C/C2=CC(OCC3=CC=C(OC(C)(C)C(N[C@@H](C(O)=O)CC(C)C)=O)C=C3)=CC(OC)=C2)C=C1
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Target
FABP; PPAR
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Purity
97.22
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Solubility
DMSO : ≥ 100 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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(E/Z) -ABP/PPAR modulator 1
(E/Z) -ABP/PPAR modulator 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.