E3 Ligase Ligand-linker Conjugate 5 [CAS 2839670-45-8]
E3 Ligase Ligand-linker Conjugate 5 [CAS 2839670-45-8]
SKU:QM-0099410
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Product Details
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Description
E3 Ligase Ligand-linker Conjugate 5 is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide and the corresponding Linker. E3 Ligase Ligand-linker Conjugate 5 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
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CAS Number
[2839670-45-8]
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Molecular Formula
C29H37N5O6
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Molecular Weight
551.63
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Smiles
O=C1NC(CCC1N2C(C3=C(C=CC(N4CCC(CC4)CN5CC6(CN(C6)C(OC(C)(C)C)=O)C5)=C3)C2=O)=O)=O
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Target
E3 Ligase Ligand-Linker Conjugates
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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E3 Ligase Ligand-linker Conjugate 5 [CAS 2839670-45-8]
E3 Ligase Ligand-linker Conjugate 5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.