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EGFR/ErbB-2/ErbB-4 inhibitor-3 [CAS 881001-19-0]

EGFR/ErbB-2/ErbB-4 inhibitor-3 [CAS 881001-19-0]

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QM-0077796-01

£607.68 GBP
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Product Details

  • Description

    EGFR/ErbB-2/ErbB-4 inhibitor-3 (compound 29) is a potent tyrosine kinase inhibitor with IC50s of 0.3, 1.1, 0.5, 2.5, 24 nM for erbB1, erbB2, erbB4, EGF, HER, respectively[1]. EGFR/ErbB-2/ErbB-4 inhibitor-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

  • CAS Number

    [881001-19-0]

  • Molecular Formula

    C17H11ClFN5O

  • Molecular Weight

    355.75

  • Smiles

    O=C(C#CC)NC1=CC(C(NC(C=C2)=CC(Cl)=C2F)=NC=N3)=C3C=N1

  • Target

    EGFR

  • Isoform

    EGFR/ErbB1/HER1; ErbB2/HER2; ErbB4/HER4

  • Concentration

    10mM

  • Purity

    98.19

  • Solubility

    DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
5 mgQM-0077796-01
5 mgQM-0077796-01
£607.68/ea		 £0.00
£607.68/ea £0.00
10 mgQM-0077796-02
10 mgQM-0077796-02
£885.92/ea		 £0.00
£885.92/ea £0.00
25 mgQM-0077796-03
25 mgQM-0077796-03
£1,723.06/ea		 £0.00
£1,723.06/ea £0.00
50 mgQM-0077796-04
50 mgQM-0077796-04
£2,560.19/ea		 £0.00
£2,560.19/ea £0.00
100 mgQM-0077796-05
100 mgQM-0077796-05
£3,815.28/ea		 £0.00
£3,815.28/ea £0.00
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EGFR/ErbB-2/ErbB-4 inhibitor-3 [CAS 881001-19-0]

EGFR/ErbB-2/ErbB-4 inhibitor-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.