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EGFR kinase inhibitor 1 [CAS 2413958-04-8]
EGFR kinase inhibitor 1 [CAS 2413958-04-8]
SKU:QM-0065183
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Product Details
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Description
EGFR kinase inhibitor 1 is a potent EGFR inhibitor with IC50s of 37, 1.7, >300 nM for WT, l885R/T790M, L858R/T790M/C797S, respectively. EGFR kinase inhibitor 1 induces apoptosis and cell cycle arrest at G0/G1-phase. EGFR kinase inhibitor 1 inhibits the cell motility. EGFR kinase inhibitor 1 shows antiproliferative and anti-tumor activity[1].
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CAS Number
[2413958-04-8]
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Molecular Formula
C30H31N7O2
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Molecular Weight
521.61
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Smiles
C=CC(NC1=C(C=C(C(NC2=NC(C3=CN(C4=C3C=CC=C4)C)=CC=N2)=C1)OC)N5C=CC=C5CN(C)C)=O
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Target
Apoptosis; EGFR
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Isoform
EGFR/ErbB1/HER1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR kinase inhibitor 1 [CAS 2413958-04-8]
EGFR kinase inhibitor 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.