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EGFR kinase inhibitor 7
EGFR kinase inhibitor 7
SKU:QM-0121202
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Product Details
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Description
EGFR kinase inhibitor 7 (compound 18i) is an EGFR inhibitor (IC50=42.3 nM) with anticancer activity. EGFR kinase inhibitor 7 has significant in vitro cytotoxicity and apoptosis induction ability. EGFR kinase inhibitor 7 has antiproliferative activity against human colon cancer cell line HCT116 and human non-small cell lung cancer cell line A549, with IC50 values of 4.82 µM and 1.43 µM, respectively[1].
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Molecular Formula
C28H26Cl2FN3O3SSe
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Molecular Weight
653.45
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Smiles
O=C(C1=C([Se]C2=CC=C(F)C(Cl)=C2)SC(C)=C1C3=CC=CC(Cl)=C3)NC(C)C(N4CCN(C(C=C)=O)CC4)=O
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Target
Apoptosis; EGFR
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Isoform
EGFR/ErbB1/HER1
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Shipping Conditions
Room temperature
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EGFR kinase inhibitor 7
EGFR kinase inhibitor 7 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.