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EGFR ligand-2 [CAS 2737283-20-2]
EGFR ligand-2 [CAS 2737283-20-2]
SKU:QM-0069102
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Product Details
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Description
EGFR ligand-2 (compound C4), a covalent EGFR ligand, is a EGFR mutant inhibitor with IC50s of 21 nM and 48 nM for EGFRL858R and EGFRL858R/T790M, respectively. EGFR ligand-2 can be used to synthesize PROTAC[1].
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CAS Number
[2737283-20-2]
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Molecular Formula
C30H35N9O
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Molecular Weight
537.66
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Smiles
C=CC(N1CCC[C@@H](C1)N2C(NC3=CC=CC=C3)=NC4=CN=C(N=C42)NC5=CC=C(C=C5)N6CCN(CC6)C)=O
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Target
EGFR
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Isoform
EGFR/ErbB1/HER1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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EGFR ligand-2 [CAS 2737283-20-2]
EGFR ligand-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.