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EP4 receptor antagonist 1 [CAS 2287259-07-6]
EP4 receptor antagonist 1 [CAS 2287259-07-6]
SKU:QM-0144331-01
£214.03 GBP
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Product Details
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Description
EP4 receptor antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist for cancer immunotherapy. EP4 receptor antagonist 1 inhibits human and mouse EP4 receptor with IC50s of 6.1 nM and 16.2 nM, respectively. IC50s >10 μM for human EP1, EP2, and EP3 receptors[1].
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CAS Number
[2287259-07-6]
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Molecular Formula
C23H21F3N4O3
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Molecular Weight
458.43
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Smiles
O=C(O)C1=CC=C([C@@H](NC(C2=C(/C=C/C)N=NN2CC3=CC=C(C(F)(F)F)C=C3)=O)C)C=C1
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Target
Prostaglandin Receptor
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Isoform
EP
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Purity
99.66
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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EP4 receptor antagonist 1 [CAS 2287259-07-6]
EP4 receptor antagonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.