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ERBB agonist-1 [CAS 930856-19-2]

ERBB agonist-1 [CAS 930856-19-2]

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QM-0008494-01

£135.25 GBP
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Product Details

  • Description

    ERBB agonist-1 (Compound EF-1) is an agonist for ERBB4, that activates the ERBB4 signaling pathway by inducing dimerization of the ERBB4 receptor with an EC50 of 10.5 μM. ERBB agonist-1 induces phosphorylation of Akt and ERK1/2, reduces the collagen expression in cardiac fibroblasts, inhibits H2O2-induced cardiomyocyte death and Ang II -induced cardiomyocyte hypertrophy. ERBB agonist-1 prevents fibrosis and exhibits cardioprotective efficacy in mouse models[1].

  • CAS Number

    [930856-19-2]

  • Molecular Formula

    C24H25N3O2S

  • Molecular Weight

    419.54

  • Smiles

    O=C(NC1CC1)C(SC(N2C3CCCC3)=NC4=CC=CC=C4C2=O)C5=CC=CC=C5

  • Target

    Akt; EGFR; ERK

  • Purity

    99.16

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
5 mgQM-0008494-01
5 mgQM-0008494-01
£88.20
£135.25/ea
 £0.00
£88.20
£135.25/ea
 £0.00
10 mM - 1 mLQM-0008494-02
10 mM - 1 mLQM-0008494-02
£96.30
£145.38/ea
 £0.00
£96.30
£145.38/ea
 £0.00
10 mgQM-0008494-03
10 mgQM-0008494-03
£139.50
£238.32/ea
 £0.00
£139.50
£238.32/ea
 £0.00
25 mgQM-0008494-04
25 mgQM-0008494-04
£279.00
£426.65/ea
 £0.00
£279.00
£426.65/ea
 £0.00
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ERBB agonist-1 [CAS 930856-19-2]

ERBB agonist-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.