Estrogen receptor modulator 10 [CAS 2991504-90-4]
Estrogen receptor modulator 10 [CAS 2991504-90-4]
SKU:QM-0071774
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Product Details
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Description
Estrogen receptor modulator 10 (compound G-5b) is an estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM). Estrogen receptor modulator 10 is developed based on the Fulvestrant molecule and can rapidly degrade ER receptors through the proteasome pathway. Estrogen receptor modulator 10 can induce cell apoptosis and block cells in the G1/G0 phase and can be used in cancer research[1].
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CAS Number
[2991504-90-4]
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Molecular Formula
C32H37F9N4O3S
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Molecular Weight
728.71
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Smiles
FC(C=C(NC1CN(CCCS(CCCC(F)(F)C(F)(F)F)(=O)=O)C1)C=C2F)=C2[C@H]3N(CC(F)(F)CO)[C@H](C)CC4=C3NC5=CC=CC=C54
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Target
Bcl-2 Family; Caspase; Estrogen Receptor/ERR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Estrogen receptor modulator 10 [CAS 2991504-90-4]
Estrogen receptor modulator 10 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.