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FXR agonist 10

FXR agonist 10

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SKU:QM-0098647

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  • Description

    FXR agonist 10 (Compound 27) is an agonist for FXR with an EC50 of 14.26 μM. FXR agonist 10 upregulates the expression of SHP and BSEP proteins, downregulates the expression of NTCP and CYP7A1 proteins. FXR agonist 10 ameliorates the ANIT-induced cholestasis in mouse model[1].

  • Molecular Formula

    C15H22O4

  • Molecular Weight

    266.33

  • Smiles

    C[C@@H]1C[C@]2(O)C(C(C)(C)OO2)=C[C@]34[C@](O4)(C)CC[C@@]31[H]

  • Target

    FXR

  • Shipping Conditions

    Room temperature

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FXR agonist 10

FXR agonist 10 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.