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FXR agonist 12 [CAS 1831862-88-4]
FXR agonist 12 [CAS 1831862-88-4]
SKU:QM-0008135
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Product Details
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Description
FXR agonist 12 (Compound C7) is the orally active agonist for FXR. FXR agonist 12 down-regulates bile acid synthesis-related genes, and up-regulates bile acid transport-related genes in HepG2 cells. FXR agonist 12 improves ANIT-induced cholestasis, ameliorates the liver damage and fibrosis in mouse NASH models[1].
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CAS Number
[1831862-88-4]
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Molecular Formula
C26H44O3
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Molecular Weight
404.63
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Smiles
C[C@@]12[C@]3([H])[C@]([C@@H]([C@@H]([C@]1([H])CCCC2)CC)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCC(O)=O)C
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Target
FXR
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Shipping Conditions
Room temperature
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FXR agonist 12 [CAS 1831862-88-4]
FXR agonist 12 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.