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FXR agonist 15 [CAS 2991276-14-1]
FXR agonist 15 [CAS 2991276-14-1]
SKU:QM-0016253
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Product Details
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Description
FXR agonist 15 is a selective, potent and orally active farnesoid X receptor (FXR) agonist with EC50 of 0.76 μM. FXR agonist 15 exhibits no obvious activation on other nuclear receptors including LXRα/β, PXR, PPARα/β/γ, THR-β, with EC50 values all >10 μM. FXR agonist 15 can alleviate steatosis, lobular inflammation, hepatocyte ballooning and liver fibrosis. FXR agonist 15 can be used for the research of nonalcoholic steatohepatitis (NASH) [1].
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CAS Number
[2991276-14-1]
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Molecular Formula
C24H22Cl2FNO5S
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Molecular Weight
526.4
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Smiles
FC1=CC(C2=CC=C(N(S(=O)(C3=C(Cl)C=CC=C3Cl)=O)CC(C)C)C=C2)=CC=C1OCC(O)=O
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Target
FXR
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Shipping Conditions
Room temperature
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FXR agonist 15 [CAS 2991276-14-1]
FXR agonist 15 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.