FZD7 antagonist 1 [CAS 2416664-25-8]

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SKU:QM-0075713

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Description
FZD7 antagonist 1 (peptide 34) is a dFz7-21 analogue. FZD7 antagonist 1 is an FZD7 antagonist that inhibits the wnt3a with IC50 value of 9.2 nM. FZD7 antagonist 1 blocks TcdB−FZD interaction via targeting FZD receptors[1].
CAS Number
[2416664-25-8]
Molecular Formula
C142H202N32O42S4
Molecular Weight
3157.57
Smiles
O=C(C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC1=CC=C(O)C=C1)=O)CCSC)=O)[C@H](CC)C)=O)CC2=CNC=N2)=O)CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)[C@@H](C)O)=O)CC(O)=O)=O)CC(O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CC(C)C)=O)CC3=CNC4=CC=CC=C34)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC5=CC=C(O)C=C5)=O)CCSC)=O)[C@H](CC)C)=O)CC6=CNC=N6)=O)=O)CC7=CNC8=CC=CC=C78)=O)CC(C)C)=O)CCC(O)=O)=O)CC(C)C)=O)CC(O)=O)=O)CC(O)=O)=O)[C@@H](C)O
Target
Wnt
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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FZD7 antagonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.