Glucocorticoid receptor modulator 3 [CAS 2688785-13-7]
Glucocorticoid receptor modulator 3 [CAS 2688785-13-7]
SKU:QM-0153594
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Product Details
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Description
Glucocorticoid receptor modulator 3 (Payload 6) is a thioester-containing glucocorticoid receptor modulator (IC50=0.6 nM) . Glucocorticoid receptor modulator 3 is designed to inactivate unconjugated payloads rapidly through liver metabolism, thereby minimizing systemic exposure. Glucocorticoid receptor modulator 3 can be utilized in the development of antibody-drug conjugates (ADCs) targeting autoimmune diseases[1].
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CAS Number
[2688785-13-7]
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Molecular Formula
C29H32F3NO5S
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Molecular Weight
563.63
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Smiles
O=C([C@@]1(OC(C2=CC(N)=C(C=C2)F)=O)[C@@H](C[C@@]3([C@]1(C)C[C@H](O)[C@]4(F)[C@@]5(C)C=CC(C=C5CC[C@]43[H])=O)[H])C)SCF
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Target
Glucocorticoid Receptor
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Shipping Conditions
Room temperature
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Glucocorticoid receptor modulator 3 [CAS 2688785-13-7]
Glucocorticoid receptor modulator 3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.