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Glucocorticoid receptor modulator 4 [CAS 2688785-30-8]

Glucocorticoid receptor modulator 4 [CAS 2688785-30-8]

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QM-0125647

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Product Details

  • Description

    Glucocorticoid receptor modulator 4 (Compound DL5) is a conjugate of a linker and a glucocorticoid receptor modulator. Glucocorticoid receptor modulator 4 exhibits GRE Reporter activity in mTNF expressing K562 cell with an EC50 of 40 μM. Glucocorticoid receptor modulator 4 binds with an anti-tumor necrosis factor (TNF) antibody, and exhibits anti-inflammtory activity against arthritis in mouse models[1].

  • CAS Number

    [2688785-30-8]

  • Molecular Formula

    C37H43BrF3N3O8S

  • Molecular Weight

    826.72

  • Smiles

    O=C(O[C@]1(C(SCF)=O)[C@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)=O)C5=CC=C(F)C(NC([C@@H](NC([C@@H](NC(CBr)=O)C)=O)C)=O)=C5

  • Target

    Drug-Linker Conjugates for ADC; Glucocorticoid Receptor

  • Shipping Conditions

    Room temperature
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1 EachQM-0125647
1 EachQM-0125647
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Glucocorticoid receptor modulator 4 [CAS 2688785-30-8]

Glucocorticoid receptor modulator 4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.