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GluN2B-NMDAR antagonist-2
GluN2B-NMDAR antagonist-2
SKU:QM-0116235
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Product Details
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Description
GluN2B-NMDAR antagonist-2 (compound S-58) is a potent, selective and cross the blood-brain barrier NMDAR-GluN2B antagonist with an IC50 value of 74.01, nM. GluN2B-NMDAR antagonist-2 shows mild cytotoxicity. GluN2B-NMDAR antagonist-2 decreases the cerebral infarction rates and neurologic deficit scores. GluN2B-NMDAR antagonist-2 has the potential for the research of stroke[1].
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Molecular Formula
C24H25Cl2N3O3
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Molecular Weight
474.38
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Smiles
O=C(C1=CC=CC=C12)O[C@H]2CCCN(CC3)CCN3C(C4=CC(C=CC=C5Cl)=C5N4)=O.Cl
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Target
IGluR
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Isoform
NMDA Receptor
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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GluN2B-NMDAR antagonist-2
GluN2B-NMDAR antagonist-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.