GPR40 agonist 5 [CAS 2443384-60-7]
GPR40 agonist 5 [CAS 2443384-60-7]
SKU:QM-0067479
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Product Details
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Description
GPR40 agonist 5 (compound I-14) is an orally active and potent GPR40 (G protein coupled receptor 40) agonist, with an EC50 of 47 nM. GPR40 agonist 5 decreases the levels of blood glucose and improves the glucose tolerance. GPR40 agonist 5 has sufficient effectiveness for the control of hyperglycemia state in type 2 diabetic mice[1]. GPR40 agonist 5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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CAS Number
[2443384-60-7]
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Molecular Formula
C27H24N2O4
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Molecular Weight
440.49
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Smiles
CC#CC(C1=CC=C(C=C1)OCC2=CN3C=C(N=C3C=C2)C4=CC=C(C=C4)OC)CC(O)=O
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Target
Free Fatty Acid Receptor
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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GPR40 agonist 5 [CAS 2443384-60-7]
GPR40 agonist 5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.