GPR84 antagonist 2 [CAS 2244269-74-5]
GPR84 antagonist 2 [CAS 2244269-74-5]
SKU:QM-0148675-01
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Product Details
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Description
GPR84 antagonist 2 (compound 33) is a potent, selective, and orally active GPR84 antagonist (IC50=8.95 nM) . GPR84 antagonist 2 shows improved potency in the calcium mobilization assay and the ability to inhibit the chemotaxis of neutrophils and macrophages upon GPR84 activation. GPR84 antagonist 2 has the potential for the research of ulcerative colitis[1].
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CAS Number
[2244269-74-5]
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Molecular Formula
C28H16Cl2NaO4PS2
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Molecular Weight
605.42
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Smiles
O=P(OC1=CC2=C(SC3=C1C=CC=C3)C=CC=C2Cl)(OC4=CC5=C(SC6=C4C=CC=C6)C=CC=C5Cl)O[Na]
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Target
GPR84
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Concentration
10mM
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Purity
99.06
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Solubility
DMSO : 125 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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GPR84 antagonist 2 [CAS 2244269-74-5]
GPR84 antagonist 2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.