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GSK-3β inhibitor 15
GSK-3β inhibitor 15
SKU:QM-0068444
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Product Details
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Description
GSK-3β inhibitor 15 (Compound 54) is a GSK-3β inhibitor (IC50: 3.4 nM) . GSK-3β inhibitor 15 inhibits Aβ1-42-induced GSK-3β and tau protein phosphorylation. GSK-3β inhibitor 15 inhibits LPS-induced iNOS expression. GSK-3β inhibitor 15 has neuroprotective effects on Aβ1-42-induced neurotoxicity. GSK-3β inhibitor 15 can be used for research of Alzheimer’s disease (AD) [1].
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Molecular Formula
C17H16N6OS
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Molecular Weight
352.41
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Smiles
O=C(CCN1N=CC(C)=C1)NC2=NNC3=C2SC(C4=CN=CC=C4)=C3
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Target
Apoptosis; GSK-3; Tau Protein
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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GSK-3β inhibitor 15
GSK-3β inhibitor 15 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.