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GSK-3β inhibitor 23
GSK-3β inhibitor 23
SKU:QM-0009367
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Product Details
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Description
GSK-3β inhibitor 23 (Compound 11726169) is the inhibitor for glycogen synthase kinase-3, that inhibits GSK-3β and GSK-3α with IC50 of 12.1 nM and 18.8 nM. GSK-3β inhibitor 23 exhibits antiviral activity against HIV 1. GSK-3β inhibitor 23 exhibits good metabolic stablility in mouse/human liver microsomes and plasma, but poor Caco-2 permeability (which predicts low oral bioavailability) [1].
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Molecular Formula
C18H13Cl2N5O2S
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Molecular Weight
434.3
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Smiles
ClC1=CC(Cl)=CC(NC2=NN(S(C3=CC=C(C=CC=C4)C4=C3)(=O)=O)C(N)=N2)=C1
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Target
GSK-3
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Isoform
GSK-3α; GSK-3β
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Shipping Conditions
Room temperature
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GSK-3β inhibitor 23
GSK-3β inhibitor 23 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.