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GSK-3β inhibitor 27
GSK-3β inhibitor 27
SKU:QM-0011843
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Product Details
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Description
GSK-3β inhibitor 27 (Compound 1c) is a reversible and competitive GSK-3β inhibitor with an IC50 value of 2.2 μM. GSK-3β inhibitor 27 inhibits tau hyperphosphorylation, reduces Aβ protein aggregation and possesses metal chelation and neuroprotective potential. GSK-3β inhibitor 27 is promising for research of neurodegenerative diseases (such as Alzheimer’s disease) [1].
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Molecular Formula
C16H17ClN4O2
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Molecular Weight
332.78
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Smiles
O=C(N(CC1=CC=C(Cl)C=C1)C)/C=C\C(NC2=NNC(C)=C2)=O
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Target
Amyloid-β; GSK-3
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Isoform
GSK-3β
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Shipping Conditions
Room temperature
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GSK-3β inhibitor 27
GSK-3β inhibitor 27 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.