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Hh Pathway-IN-1 [CAS 599150-20-6]

Hh Pathway-IN-1 [CAS 599150-20-6]

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SKU:QM-0112587-01

£78.82 GBP
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  • Description

    Hh Pathway-IN-1, a Hedgehog (Hh) pathway inhibitor, is a potent Gli antagonist. Hh Pathway-IN-1 inhibits Hh pathway functional with an IC50 value of 1.1 µM in C3H10T1/2 cells. Hh Pathway-IN-1 does not inhibit Wnt signaling. Hh Pathway-IN-1 shows anti-proliferative activity. Hh Pathway-IN-1 decreases the GLI1 mRNA expression. Hh Pathway-IN-1 inhibits colony formation in a dose-dependent manner[1][2].

  • CAS Number

    [599150-20-6]

  • Molecular Formula

    C27H29NO6

  • Molecular Weight

    463.53

  • Smiles

    COCCOC(C1=C(C)NC(CC(C2=C(C=CC=C2)OC)CC3=O)=C3C1C4=CC(O)=CC=C4)=O

  • Target

    Gli; Hedgehog

  • Purity

    99.06

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H400

  • Precautions

    H302, H400

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Variant Variant total Quantity Price Variant total
1 mgQM-0112587-01
1 mgQM-0112587-01
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5 mgQM-0112587-02
5 mgQM-0112587-02
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10 mgQM-0112587-03
10 mgQM-0112587-03
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25 mgQM-0112587-04
25 mgQM-0112587-04
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50 mgQM-0112587-05
50 mgQM-0112587-05
£605.25/ea
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£605.25/ea £0.00
100 mgQM-0112587-06
100 mgQM-0112587-06
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Hh Pathway-IN-1 [CAS 599150-20-6]

Hh Pathway-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.