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HIV-1 inhibitor-16 [CAS 2719675-72-4]

HIV-1 inhibitor-16 [CAS 2719675-72-4]

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SKU:QM-0065685

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  • Description

    HIV-1 inhibitor-16 (compound 7a) is a highly potent HIV-1 inhibitor with an EC50 value of 1.3 nM for HIV-1 WT. HIV-1 inhibitor-16 also has certain inhibitory activity against HIV-1 K103N, E138K, Y181C and L100I strains with EC50s of 5.4 nM, 9.2 nM, 22 nM and 35 nM. HIV-1 inhibitor-16 has favorable solubility and liver microsome stability, and does not exhibit apparent CYP enzymatic inhibitory activity or acute toxicity[1].

  • CAS Number

    [2719675-72-4]

  • Molecular Formula

    C23H16F2N6

  • Molecular Weight

    414.41

  • Smiles

    N#CC1=CC=C(NC2=NC=C(C)C(NC3=C(F)C=C(C4=CC=NC=C4)C=C3F)=N2)C=C1

  • Target

    HIV

  • Isoform

    HIV-1

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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HIV-1 inhibitor-16 [CAS 2719675-72-4]

HIV-1 inhibitor-16 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.