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HIV-1 inhibitor-21 [CAS 2554620-04-9]
HIV-1 inhibitor-21 [CAS 2554620-04-9]
SKU:QM-0066515
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Product Details
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Description
HIV-1 inhibitor-21 (compound 9b) is a potent HIV-1 non-nucleoside reverse transcriptase (RT) inhibitor, with an IC50 value of 0.55 μM for HIV-1 RT. HIV-1 inhibitor-21 has antiretroviral activity against HIV-1 WT and K103N strains with EC50s of 12.7 nM and 10.4 nM, and has relatively low cytotoxicity (MT-4 cells CC50 =10.2 μM) [1].
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CAS Number
[2554620-04-9]
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Molecular Formula
C28H24N6O2
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Molecular Weight
476.53
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Smiles
N#CC1=CC=C(NC2=NC(NC3=C(C)C=C(/C=C/C#N)C=C3C)=C4C=C(OC)C(OC)=CC4=N2)C=C1
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Target
HIV
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Isoform
HIV-1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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HIV-1 inhibitor-21 [CAS 2554620-04-9]
HIV-1 inhibitor-21 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.