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HIV-1 inhibitor-24 [CAS 2475658-75-2]
HIV-1 inhibitor-24 [CAS 2475658-75-2]
SKU:QM-0066519
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Product Details
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Description
HIV-1 inhibitor-24 (compound S-12a) is a highly potent HIV-1 reverse transcriptase, with an IC50 value of 9.5 nM. HIV-1 inhibitor-24 has high antiretroviral activity against WT HIV-1 with an EC50 of 1.6 nM, and exhibits relatively low cytotoxicity with a CC50 of 9.07 μM in MT-4 cells. HIV-1 inhibitor-24 is well tolerated at a dose of 2 g/kg in mice and has a significant cardiovascular safety[1].
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CAS Number
[2475658-75-2]
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Molecular Formula
C26H19N5O2
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Molecular Weight
433.46
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Smiles
N#CC1=CC=C(C2=CC=C([C@@H](C3=NC(NC4=CC=C(C#N)C=C4)=NC=C3)O)C(OC)=C2)C=C1
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Target
HIV
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Isoform
HIV-1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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HIV-1 inhibitor-24 [CAS 2475658-75-2]
HIV-1 inhibitor-24 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.