HIV-1 inhibitor-25 [CAS 2475658-74-1]
HIV-1 inhibitor-25 [CAS 2475658-74-1]
SKU:QM-0066520
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Product Details
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Description
HIV-1 inhibitor-25 (compound R-12a) is a highly potent HIV-1 reverse transcriptase, with an IC50 value of 0.1061 μM. HIV-1 inhibitor-25 has high antiretroviral activity against WT HIV-1 with an EC50 of 13.6 nM, and exhibits relatively low cytotoxicity with a CC50 of 33.13 μM in MT-4 cells. HIV-1 inhibitor-25 also has inhibitory activity against HIV-1 mutant strains (L100I, K103N, Y181C, Y188L, E138K, F227L+V106A) with EC50 of 0.1961 ~ 5.8136 μM. HIV-1 inhibitor-25 can be used for researching AIDS[1].
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CAS Number
[2475658-74-1]
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Molecular Formula
C26H19N5O2
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Molecular Weight
433.46
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Smiles
N#CC1=CC=C(C2=CC=C([C@H](C3=NC(NC4=CC=C(C#N)C=C4)=NC=C3)O)C(OC)=C2)C=C1
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Target
HIV
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Isoform
HIV-1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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HIV-1 inhibitor-25 [CAS 2475658-74-1]
HIV-1 inhibitor-25 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.