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HIV-1 inhibitor-40 [CAS 2789676-44-2]
HIV-1 inhibitor-40 [CAS 2789676-44-2]
SKU:QM-0067590
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Product Details
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Description
HIV-1 inhibitor-40 (Compound 4ab) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 with an EC50 of 1.9 nM. HIV-1 inhibitor-40 displays weak CYP sensitivity with IC50 values of 5.16 μM and 4.51 μM against CYP2C9 and CYP2C19, respectively. HIV-1 inhibitor-40 has no apparent in vivo acute toxicity[1].
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CAS Number
[2789676-44-2]
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Molecular Formula
C25H18N6O2
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Molecular Weight
434.45
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Smiles
NC1=NC(NC2=CC=C(C=C2)C#N)=NC(OC(C=CC(C3=CC=C(C=C3)C#N)=C4)=C4OC)=C1
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Target
Cytochrome P450; HIV
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Isoform
CYP2; HIV-1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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HIV-1 inhibitor-40 [CAS 2789676-44-2]
HIV-1 inhibitor-40 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.