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HIV-1 inhibitor-58 [CAS 3034064-68-8]
HIV-1 inhibitor-58 [CAS 3034064-68-8]
SKU:QM-0068659
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Product Details
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Description
HIV-1 inhibitor-58 (Compound 10c) is a broad-spectrum antiviral agent. HIV-1 inhibitor-58 is a non-nucleoside reverse transcriptase inhibitor. HIV-1 inhibitor-58 inhibits WT strain IIIB, NNRTI-resistant strains (such as K103N and E138K) in MT-4 cells, with EC50 less than 50 nM. HIV-1 inhibitor-58 also inhibits CYP2C9 and CYP2C19 (IC50: 2.06 μM, 1.91 μM) . HIV-1 inhibitor-58 can be used for HIV infection reserch[1].
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CAS Number
[3034064-68-8]
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Molecular Formula
C26H24N6O2
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Molecular Weight
452.51
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Smiles
CC1=CC(C#N)=CC(C)=C1OC2=C3CN(CCC3=NC(NC4=CC=C(C=C4)C#N)=N2)C(CC)=O
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Target
Cytochrome P450; HIV; Reverse Transcriptase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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HIV-1 inhibitor-58 [CAS 3034064-68-8]
HIV-1 inhibitor-58 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.