HIV-1 inhibitor-6 [CAS 1821309-39-0]
HIV-1 inhibitor-6 [CAS 1821309-39-0]
SKU:QM-0144862-01
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Product Details
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Description
HIV-1 inhibitor-6 (compound 9), a diheteroarylamide-based compound, is a potent HIV-1 pre-mRNA alternative splicing inhibitor. HIV-1 inhibitor-6 blocks HIV replication. HIV-1 inhibitor-6 is active against wild-type HIV-1IIIB (subtype B, X4-tropic) and HIV-1 97USSN54 (subtype A, R5-tropic) with EC50s of 0.6 μM and 0.9 μM, respectively. HIV-1 inhibitor-6 inhibits HIV strains resistant to agents targeting HIV reverse transcriptase, protease, integrase, and coreceptor CCR5 with EC50s ranging from 0.9 to 1.5 μM[1].
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CAS Number
[1821309-39-0]
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Molecular Formula
C14H10N4O4S
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Molecular Weight
330.32
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Smiles
O=C(C1=CN(C)C=CC1=O)NC2=NSC3=C2C=C([N+]([O-])=O)C=C3
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Target
HIV
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Isoform
HIV-1
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Purity
99.1
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Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 80°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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HIV-1 inhibitor-6 [CAS 1821309-39-0]
HIV-1 inhibitor-6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.