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HIV-1 integrase inhibitor 12
HIV-1 integrase inhibitor 12
SKU:QM-0087072
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Product Details
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Description
HIV-1 integrase inhibitor 12 (Compound 17) is an inhibitor for HIV-1 integrase with an IC50 of 1.4 nM. HIV-1 integrase inhibitor 12 inhibits the HIV-1 WT and HIV-1 T125A, with IC50 of 7.4 and 120 nM, respectively. HIV-1 integrase inhibitor 12 exhibits metabolic stability and Caco-2 permeability, and good pharmacokinetic characteristics with good bioavailability (64%) and low clearance (0.16 L/hr/kg) in rats[1].
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Molecular Formula
C29H43NO4
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Molecular Weight
469.66
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Smiles
CC1=CC(C(NC2CCCCC2)=O)=C(C3=C1[C@@H](C(O)=O)OC(C)(C)C)CC[C@]43CC[C@H](C)CC4
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Target
HIV Integrase
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Shipping Conditions
Room temperature
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HIV-1 integrase inhibitor 12
HIV-1 integrase inhibitor 12 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.