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HPGDS inhibitor 3 [CAS 2255311-93-2]
HPGDS inhibitor 3 [CAS 2255311-93-2]
SKU:QM-0067012
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Product Details
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Description
HPGDS inhibitor 3 is an orally active and highly potent peripherally restricted hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 value of 9.4 nM and EC50 of 42 nM, respectively. HPGDS inhibitor 3 exhibits good selectivity, good pharmacokinetic parameters in mouse, rat, and dog, and no CNS toxicity. HPGDS inhibitor 3 has anti-inflammatory activity[1].
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CAS Number
[2255311-93-2]
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Molecular Formula
C21H27N3O2
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Molecular Weight
353.46
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Smiles
CC(O)([C@H]1CC[C@@H](CC1)NC(C2=CC3=CC=C(N=C3N=C2)C4CC4)=O)C
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Target
PGE synthase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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HPGDS inhibitor 3 [CAS 2255311-93-2]
HPGDS inhibitor 3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.