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HSMG-1 inhibitor 11j [CAS 1402452-15-6]

HSMG-1 inhibitor 11j [CAS 1402452-15-6]

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QM-0141284-01

£301.50 GBP
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Product Details

  • Description

    HSMG-1 inhibitor 11j, a pyrimidine derivative, is a potent and selective inhibitor of hSMG-1, with an IC50 of 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over mTOR (IC50=50 nM), PI3Kα/γ (IC50=92/60 nM) and CDK1/CDK2 (IC50=32/7.1 μM) . hSMG-1 inhibitor 11j can be used for the research of cancer[1].

  • CAS Number

    [1402452-15-6]

  • Molecular Formula

    C27H28ClN7O3S

  • Molecular Weight

    566.07

  • Smiles

    O=S(C1=CC(NC2=NC=CC(C3=CC(C4=CC=C(NC(NC)=O)C=C4)=NC=C3)=N2)=CC=C1Cl)(N(CC)CC)=O

  • Target

    CDK; GSK-3; mTOR; PI3K

  • Isoform

    CDK1; CDK2; mTOR; PI3Kα; PI3Kγ

  • Purity

    99.82

  • Solubility

    DMSO : 80 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture and light)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
1 mgQM-0141284-01
1 mgQM-0141284-01
£301.50/ea		 £0.00
£301.50/ea £0.00
5 mgQM-0141284-02
5 mgQM-0141284-02
£678.15/ea		 £0.00
£678.15/ea £0.00
10 mM - 1 mLQM-0141284-03
10 mM - 1 mLQM-0141284-03
£832.46/ea		 £0.00
£832.46/ea £0.00
10 mgQM-0141284-04
10 mgQM-0141284-04
£1,116.77/ea		 £0.00
£1,116.77/ea £0.00
25 mgQM-0141284-05
25 mgQM-0141284-05
£1,806.89/ea		 £0.00
£1,806.89/ea £0.00
50 mgQM-0141284-06
50 mgQM-0141284-06
£2,560.19/ea		 £0.00
£2,560.19/ea £0.00
100 mgQM-0141284-07
100 mgQM-0141284-07
£3,815.28/ea		 £0.00
£3,815.28/ea £0.00
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HSMG-1 inhibitor 11j [CAS 1402452-15-6]

HSMG-1 inhibitor 11j is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.