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IDH1 Inhibitor 2 [CAS 2244895-42-7]

IDH1 Inhibitor 2 [CAS 2244895-42-7]

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QM-0142478-01

£702.46 GBP
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Product Details

  • Description

    IDH1 Inhibitor 2 (compound 13) is a potent wild-type IDH1 inhibitor that exerts its activity through covalent modification of His315 with an IC50 value of 110 nM. IDH1 Inhibitor 2 can dose-dependently reduce the intracellular reduced glutamine metabolic flux, thereby affecting cellular metabolic homeostasis. IDH1 Inhibitor 2 can be used to study the role of IDH1 in cellular metabolic regulation and cancer development[1][2].

  • CAS Number

    [2244895-42-7]

  • Molecular Formula

    C26H22N4O

  • Molecular Weight

    406.48

  • Smiles

    N#CC1=C[C@@]2(C3=CC=CC=C3)[C@](CCC4=C2N=C(NC5=CC=CC=C5)N=C4)([H])[C@H](C)C1=O

  • Target

    Isocitrate Dehydrogenase (IDH)

  • Isoform

    IDH1

  • Purity

    99.4

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
1 mgQM-0142478-01
1 mgQM-0142478-01
£702.46/ea		 £0.00
£702.46/ea £0.00
10 mM - 1 mLQM-0142478-02
10 mM - 1 mLQM-0142478-02
£1,509.21/ea		 £0.00
£1,509.21/ea £0.00
5 mgQM-0142478-03
5 mgQM-0142478-03
£1,681.74/ea		 £0.00
£1,681.74/ea £0.00
10 mgQM-0142478-04
10 mgQM-0142478-04
£2,685.34/ea		 £0.00
£2,685.34/ea £0.00
25 mgQM-0142478-05
25 mgQM-0142478-05
£5,385.06/ea		 £0.00
£5,385.06/ea £0.00
50 mgQM-0142478-06
50 mgQM-0142478-06
£8,585.38/ea		 £0.00
£8,585.38/ea £0.00
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IDH1 Inhibitor 2 [CAS 2244895-42-7]

IDH1 Inhibitor 2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.