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ITK inhibitor 6 [CAS 2404604-06-2]
ITK inhibitor 6 [CAS 2404604-06-2]
SKU:QM-0067023
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Product Details
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Description
ITK inhibitor 6 (compound 43) is a potent and selective ITK inhibitor with IC50s of 4 nM, 133 nM, 320 nM, 2360 nM, 155 nM for ITK, BTK, JAK3, EGFR, LCK, respectively. ITK inhibitor 6 inhibits phosphorylation of PLCγ1 and ERK1/2. ITK inhibitor 6 shows antiproliferative activities[1].
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CAS Number
[2404604-06-2]
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Molecular Formula
C28H24F2N4O2
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Molecular Weight
486.51
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Smiles
C=CC(NCCOC1=C2C=C(NC2=CC(CC3=CC=CC=C3)=C1)C4=NNC5=C4C=CC(C(F)F)=C5)=O
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Target
Itk
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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ITK inhibitor 6 [CAS 2404604-06-2]
ITK inhibitor 6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.