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JNK3 inhibitor-4 [CAS 2409109-65-3]
JNK3 inhibitor-4 [CAS 2409109-65-3]
SKU:QM-0150700-01
£567.59 GBP
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Product Details
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Description
JNK3 inhibitor-4 is a potent inhibitor of JNK3 (IC50=1.0 nM) based on 2-aryl-1-pyrimidinyl-1H-imidazole-5-yl acetonitrile. JNK3 inhibitor-4 shows excellent selectivity over other protein kinases including isoforms JNK1 (IC50=143.9 nM) and JNK2 (IC50=298.2 nM) [1]. JNK3 inhibitor-4 has neuroprotective effect and predicated blood-brain barrier permeability[1].
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CAS Number
[2409109-65-3]
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Molecular Formula
C28H27N7O
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Molecular Weight
477.56
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Smiles
N#CCC1=CN=C(N1C2=NC(N[C@H]3CCCN(C3)C(C4CC4)=O)=NC=C2)C5=CC6=C(C=C5)C=CC=C6
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Target
JNK
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Isoform
JNK1; JNK2; JNK3
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Purity
99.37
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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JNK3 inhibitor-4 [CAS 2409109-65-3]
JNK3 inhibitor-4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.