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KRAS G12C inhibitor 61 [CAS 2300967-40-0]
KRAS G12C inhibitor 61 [CAS 2300967-40-0]
SKU:QM-0072462
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Product Details
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Description
KRAS G12C inhibitor 61 (Example 3) inhibits phospho-ERK 1/2 in MIA PaCa-2 cells with an IC50 value of 9 nM. KRAS G12C inhibitor 61 can be used for research of pancreatic, colorectal, and lung cancers[1].
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CAS Number
[2300967-40-0]
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Molecular Formula
C31H33ClFN7O2
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Molecular Weight
590.09
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Smiles
O=C1N=C(N2[C@@H](C)CN([C@H](C)C2)C(C=C)=O)C3=C(N1C4=C(C)C=CN=C4C(C)C)N=C(C5=C(N)C=CC=C5F)C(Cl)=C3
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Target
ERK; Ras
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Isoform
K-Ras
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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KRAS G12C inhibitor 61 [CAS 2300967-40-0]
KRAS G12C inhibitor 61 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.