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Kv7.2/Kv7.3 agonist 1 [CAS 2315450-35-0]
Kv7.2/Kv7.3 agonist 1 [CAS 2315450-35-0]
SKU:QM-0076253
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Product Details
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Description
Kv7.2/Kv7.3 agonist 1 (Compound 16) is an orally active agonist for KV7.2/7.3 channel (KCNQ2/3) with an EC50 of 1.03 μM. Kv7.2/Kv7.3 agonist 1 exhibits analgesic efficacy in mice chronic constriction injury (CCI) model and mice Streptozotocin -induced diabetic peripheral neuropathic pain (DPNP) model, with ED50 of 12.02 and 9.63 mg/kg[1].
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CAS Number
[2315450-35-0]
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Molecular Formula
C14H14FN3O2
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Molecular Weight
275.28
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Smiles
CC(NC1=NC(OCC2=CC=C(F)C=C2)=CC=C1N)=O
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Target
Potassium Channel
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Isoform
Voltage-gated potassium channel
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Shipping Conditions
Room temperature
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Kv7.2/Kv7.3 agonist 1 [CAS 2315450-35-0]
Kv7.2/Kv7.3 agonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.