LIN28 inhibitor LI71 enantiomer [CAS 956189-58-5]
LIN28 inhibitor LI71 enantiomer [CAS 956189-58-5]
SKU:QM-0140999-01
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Product Details
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Description
LIN28 inhibitor LI71 enantiomer is the less active enantiomer of LIN28 inhibitor LI71. LIN28 inhibitor LI71 is a LIN28 inhibitor that effectively inhibits LIN28:let-7 binding (IC50: 7 μM). LIN28 inhibitor LI71 can abolish LIN28-mediated oligouridylation of let-7 precursor (IC50: 27 μM). LIN28 inhibitor LI71 has potential application value in LIN28-driven cancer research. LIN28 inhibitor LI71 inhibits the interaction of cold shock protein of Plasmodium falciparum (PfCoSP) with DNA and α/β tubulin and has an inhibitory effect on Plasmodium falciparum[1][2].
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CAS Number
[956189-58-5]
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Molecular Formula
C21H21NO3
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Molecular Weight
335.4
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Smiles
O=C(O)C1=CC=C([C@H]2NC3=C(C=CC=C3OCC)[C@]4([H])[C@@]2([H])CC=C4)C=C1
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Target
Drug Isomer; MicroRNA; Parasite
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Purity
99.68
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Solubility
DMSO : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H312, H332
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Precautions
H302, H312, H332
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LIN28 inhibitor LI71 enantiomer [CAS 956189-58-5]
LIN28 inhibitor LI71 enantiomer is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.