LSKL, Inhibitor of Thrombospondin (TSP-1) [CAS 283609-79-0]
LSKL, Inhibitor of Thrombospondin (TSP-1) [CAS 283609-79-0]
SKU:QM-0169989-01
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Product Details
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Description
LSKL, Inhibitor of Thrombospondin (TSP-1) is a latency-associated protein (LAP) -TGFβ derived tetrapeptide and a competitive TGF-β1 antagonist. LSKL, Inhibitor of Thrombospondin (TSP-1) inhibits the binding of TSP-1 to LAP and alleviates renal interstitial fibrosis and hepatic fibrosis. LSKL, Inhibitor of Thrombospondin (TSP-1) suppresses subarachnoid fibrosis via inhibition of TSP-1-mediated TGF-β1 activity, prevents the development of chronic hydrocephalus and improves long-term neurocognitive defects following subarachnoid hemorrhage (SAH) . LSKL, Inhibitor of Thrombospondin (TSP-1) can readily crosse the blood-brain barrier[1][2].
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CAS Number
[283609-79-0]
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Molecular Formula
C21H42N6O5
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Molecular Weight
458.6
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Smiles
CC(C)C[C@@H](C(N)=O)NC([C@H](CCCCN)NC([C@H](CO)NC([C@H](CC(C)C)N)=O)=O)=O
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Target
TGF-β Receptor
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Purity
99.84
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Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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LSKL, Inhibitor of Thrombospondin (TSP-1) [CAS 283609-79-0]
LSKL, Inhibitor of Thrombospondin (TSP-1) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.