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LXRβ agonist-3 [CAS 2416049-12-0]

LXRβ agonist-3 [CAS 2416049-12-0]

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SKU:QM-0066740

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  • Description

    LXRβ agonist-3 (compound 4-13) is a potent and selective LXRβ (liver X receptor β) agonist, with an EC50 of 0.095 μM. LXRβ agonist-3 efficiently inhibits U87EGFRvIII cell, with an IC50 of 3.75 μM. LXRβ agonist-3 shows antitumor activity, and can inhibit glioblastoma[1].

  • CAS Number

    [2416049-12-0]

  • Molecular Formula

    C30H33N3O6S

  • Molecular Weight

    563.66

  • Smiles

    O=C1[C@]2(C3=CC=CC=C3N1)[C@@H](C4=CC(NC5=CC(S(C)(=O)=O)=C(C=C5)CO)=CC=C4)N(CC2)C(OC(C)(C)C)=O

  • Target

    LXR

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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LXRβ agonist-3 [CAS 2416049-12-0]

LXRβ agonist-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.