LXR agonist 4
LXR agonist 4
SKU:QM-0015922
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Product Details
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Description
LXR agonist 4 is a selective LXR inverse agonist with IC50 values of 7.6 (LXRα) and 2.9 μM (LXRβ), respectively. LXR agonist 4 exhibits selectivity over RORα and FXR. LXR agonist 4 robustly suppresses SREBP1c expression without altering ABCA1 or APOE. LXR agonist 4 displays antilipogenic properties and resolves fatty acid-induced steatosis. LXR agonist 4 can be used for the research of atherosclerosis and metabolic dysfunction-associated steatotic liver disease (MASLD) [1].
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Molecular Formula
C36H31ClF3NO2S
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Molecular Weight
634.15
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Smiles
CS(C1=CC=CC(C2=CC=C(C=C2)CN(CC(C3=CC=CC=C3)C4=CC=CC=C4)CC5=CC=CC(C(F)(F)F)=C5Cl)=C1)(=O)=O
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Target
LXR
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Shipping Conditions
Room temperature
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LXR agonist 4
LXR agonist 4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.