M3 mAChR agonist 1 [CAS 1624297-26-2]
M3 mAChR agonist 1 [CAS 1624297-26-2]
SKU:QM-0005709
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Product Details
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Description
M3 mAChR agonist 1 is an M3-preferring M3/M5 mAChR dual positive allosteric modulators (PAM) . M3 mAChR agonist 1 shows excellent subtype selectivity over other subtypes of mAChRs including M1, M2, and M4 mAChRs. M3 mAChR agonist 1 increases the contraction of isolated rat bladder strips by modulating the M3 muscarinic acetylcholine receptor, leading to enhanced signaling pathways. M3 mAChR agonist 1 can be used for the research of endocrinology[1].
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CAS Number
[1624297-26-2]
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Molecular Formula
C29H33F3N6O4S
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Molecular Weight
618.67
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Smiles
O=C(C1CCN(C2=NC=C(C(NC3=NC(C4=CC=C(OC)C(C(F)(F)F)=C4)=C(CN5[C@H](CC)CCC5)S3)=O)N=C2)CC1)O
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Target
MAChR
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Isoform
MAChR3; mAChR5
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Shipping Conditions
Room temperature
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M3 mAChR agonist 1 [CAS 1624297-26-2]
M3 mAChR agonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.